International Journal of Applied Science and Technology

ISSN 2221-0997 (Print), 2221-1004 (Online) 10.30845/ijast

Some Environmental and Socio-Economic Factors Associated to Asthma Establishment in Populations with Different Sanitary Conditions
Emilio Flores Juárez, Jorge Antonio Yáñez Santos, María Lilia Cedillo Ramirez, José Luis Morán Perales

The objective of this research was to identify environmental factors that favor asthma incidence and also, analyze the development of inflammatory processes in the lung cells induced by bacterial population present in house air with and without reports of asthma in Puebla State, México. The role of bacterial products was analyzed using the pattern of asthma Ovalbumin Antigen (OVA) in mouse and the immune response in vivo through intratracheal inoculation of lipopolysaccharide (LPS). According to the data obtained, there were cases of asthma reported only in 33 of the 217 municipalities, finding a bigger tendency to develop it in less marginal municipalities. The results indicate that different bacterial groups and their products present in air, when they are in contact with people in early development phases, block the allergic hyper response induced by allergens. All of them could explain the low level of asthma incidence in extremely marginal municipalities.

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