Antimicrobial Susceptibility Testing of Enterohaemorharrgic Escherichia coli Isolated from Rectal Swab of Cattle in Oko Oba Abattoir, Agege, Lagos.
Opere, Bolanle Olaitan; Omonigbehin, Emmanuel Adedayo; Ezeh, Abimbola Rashidat; Mbacha, Margaret Ituen; Fowora, Muinah Adenike; Smith, Stella Ifeanyi; Anwoju, Fatmah Oluwabunmi
Abstract
Fifty rectal swab samples were collected from healthy beef cattle at Oko – Oba Agege abattoir in Lagos Metropolis and were screened for the presence of enterohaemorrhagic Escherichia coli (EHEC), using standard media for Escherichia coli. Eight different antibiotics such as Gentamicin (Gen), Augmentin (Aug), Tetracycline (Tet), Ofloxacin (Ofl), Cotrimoxazole (Cot), Amoxicillin (Amx), Nalidixic acid (Nal) and Nitrofurantoin (Nitro) were used in this study. Sensitivity test was carried out by the Kirby-Bauer disc diffusion method and the efficacy of a drug was determined by measuring the diameter of the zone of inhibition that results from diffusion of the agent into the medium surrounding the disc. Antibiotic susceptibility patterns showed 44% of the isolates to be highly susceptible to the different antibiotics screened, with 56% showing multiple antibiotic resistance.
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