A new Product, BioCool®, Pested on Acne Vulgaris. Can it provide a Positive Clinical Effect?
GhonchehYazdani, Patrik Wennberg, Gunnar Sandström

Abstract
The lack of effective treatment for acne vulgaris except for long periods of treatment with antibiotics, which increases the risk of developing resistance, is vulnerable. Bio Cool® which is a medical device that has been shown to kill microorganisms in topical treatment especially on the feet. In the present study evaluation was performed to find out whether the product BioCool® alleviates acne vulgaris. Number of acne papule decreased from 25.4 ± 12.4 before the study was 18.3 ± 10.2 after 30 days of treatment (p <0.001). Patients understated even minor symptoms with DLQ after treatment (from the media point 3, IQR 4 to 1.5, IQR 4, p <0.002). The study suggests that BioCool® can have a positive clinical effect of moderate acne vulgaris. Only mild side effects occurred.

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